Choline alfoscerate
Choline alfoscerate is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Brand Name | Status | Last Update |
|---|---|---|
| choline c 11 | New Drug Application | 2024-12-17 |
| first aid shot therapy hangover relief | OTC monograph not final | 2015-06-04 |
| first aid shot therapy pain relief | OTC monograph not final | 2015-01-21 |
| gabavale-5 | unapproved drug other | 2011-08-01 |
| gabazolamine | unapproved drug other | 2011-08-18 |
| gabazolamine-0.5 | unapproved drug other | 2011-08-01 |
| gabazolpidem-5 | unapproved drug other | 2011-08-01 |
| gabitidine | unapproved drug other | 2011-08-01 |
| gaboxetine | unapproved drug other | 2011-08-01 |
| kroger cough cold and flu | OTC monograph final | 2016-06-30 |
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Clinical Trials
377 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hepatitis | D006505 | — | K75.9 | — | — | — | 1 | — | 1 |
| Cholestasis | D002779 | — | K83.1 | — | — | — | 1 | — | 1 |
| Hepatitis a | D006506 | EFO_0007305 | B15 | — | — | — | 1 | — | 1 |
| Alcoholic hepatitis | D006519 | EFO_1001345 | K70.1 | — | — | — | 1 | — | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Choline alfoscerate |
| INN | choline alfoscerate |
| Description | Choline alfoscerate is a member of the class of phosphocholines that is the choline ester of sn-glycero-3-phosphate. It is one of the major osmolyte in the renal medullary cells. It has a role as a parasympatholytic, a neuroprotective agent, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a member of sn-glycerol 3-phosphates and a member of phosphocholines. |
| Classification | Small molecule |
| Drug class | phosphoro-derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C[N+](C)(C)CCOP(=O)([O-])OC[C@H](O)CO |
Identifiers
| PDB | — |
| CAS-ID | 28319-77-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1567463 |
| ChEBI ID | 16870 |
| PubChem CID | 657272 |
| DrugBank | DB04660 |
| UNII ID | 60M22SGW66 (ChemIDplus, GSRS) |
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Safety
Black-box Warning
Black-box warning for: Gaboxetine, Nestabs, Nestabs dha, Pre-tabs dha, Sentraflox am-10, Sentravil pm-25, Sentroxatine
Adverse Events
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3,646 adverse events reported
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