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Drug ReportsCholine alfoscerate
Choline alfoscerate
Choline alfoscerate is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Status
Last Update
choline c 11New Drug Application2024-01-10
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Indications
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
N: Nervous system drugs
— N07: Other nervous system drugs in atc
— N07A: Parasympathomimetics
— N07AX: Other parasympathomimetics in atc
— N07AX02: Choline alfoscerate
HCPCS
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Clinical
Clinical Trials
321 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
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Ph 3
Ph 4
Other
Total
Alzheimer diseaseD000544EFO_0000249F03———1—1
Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCholine alfoscerate
INNcholine alfoscerate
Description
Choline alfoscerate is a member of the class of phosphocholines that is the choline ester of sn-glycero-3-phosphate. It is one of the major osmolyte in the renal medullary cells. It has a role as a parasympatholytic, a neuroprotective agent, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a member of sn-glycerol 3-phosphates and a member of phosphocholines.
Classification
Small molecule
Drug classphosphoro-derivatives
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Structure (InChI/SMILES or Protein Sequence)
C[N+](C)(C)CCOP(=O)([O-])OC[C@H](O)CO
Identifiers
PDB—
CAS-ID28319-77-9
RxCUI—
ChEMBL IDCHEMBL1567463
ChEBI ID16870
PubChem CID657272
DrugBankDB04660
UNII ID60M22SGW66 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 22,518 documents
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Safety
Black-box Warning
Black-box warning for: Gaboxetine, Nestabs, Nestabs dha, Pre-tabs dha, Sentraflox am-10, Sentravil pm-25, Sentroxatine
Adverse Events
Top Adverse Reactions
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3,282 adverse events reported
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